Trulieve Flower Review: Poison Fruit (Hybrid)

Poison Fruit is a strain that I hadn’t heard too much about before seeing it in the dispensary, but bought because it was new and happened to be available on the day that I normally pick up my medicine. There isn’t a whole lot of information available online about this strain, but Trulieve offers the following description on their product page:

Poison Fruit a cross of Durban Poison and Grapefruit. The strain produces a warm, happy, euphoric effect that is still typical of most sativa dominant hybrids making it a good choice for daytime or evening use. This strain is good for stress reduction, PTSD, some pain reducing effects should be experienced as well.

Quick Facts:

Poison Fruit (Hybrid)

Parent Strains: Durban Poison x Grapefruit 

777.0 mg THC/3.5g

0.1 mg CBD/3.5g

22.2% THC 

0.10% CBD

1.00% CBG

23.3% Total Cannabinoids


This batch of Poison Fruit was not by any means the most aesthetically pleasing bud I’ve ever seen, but the curing/moisture content was done well, as is consistent with Trulieve’s flower over the past 5-6 weeks. Poison Fruit is a mix of medium greens and darker yellows, covered in amber and brown pistils and a dusting of yellowish trichomes.

My major gripe with this batch is that like the recent batch of Zkittlez flower I picked up, there were over a dozen tiny stems spread throughout the cups. I tend to expect a couple of stems in bud; that is acceptable, but there was a disproportionate amount of small stems in this batch. Perhaps this is a hit-or-miss factor depending on the batch, but ultimately, it detracts from the final score in this category.

Appearance Rating: 3.20/5.00


Poison Fruit has a distinct taste when compared with the many other different flower strains I’ve picked up from Trulieve. The dominant smell (and taste when vaporized) is a spicy/peppery terpene(s), followed by a musky/skunky scent in the background. Looking at the Leafly pages for the parent strains, I’d have to guess that this strain picked up most of its terpene profile from its Durban Poison parent.

In some ways, there are hints of terpenes in this strain that ever so subtly remind me of Dutch Hawaiian; however, I’d have to say I enjoyed the smell and taste of that strain a good bit more than Poison Fruit. Nevertheless, Poison Fruit is an enjoyable vapor (or smoke), and should be enjoyed by connoisseurs for its unique terpene profile.

Smell/Taste Rating: 3.80/5.00

Effects/Medical Use

Though Poison Fruit is classified as a hybrid strain, I really feel it would be more appropriately labeled as a sativa. Both of its parent strains are stimulating sativas, and Poison Fruit follows suit with power cerebral and energy-inducing effects. Some patients on the Florida Medical Trees subreddit stated that this strain brought on some of the worst cannabis-induced anxiety that they had experienced in quite some time, so patients with lower tolerances should be aware of this when trying Poison Fruit for the first time.

In my experiences: After about 45 minutes, the intense and stimulating cerebral effects fade into a more mellow and subtle buzz. At this point, I could see some of the “hybrid” classification, as my body did feel pretty warm and relaxed – but not at all heavy or sleepy. Poison Fruit is definitely either a sativa-dominant hybrid or a pure sativa. The latter classification would have never caused me to think twice.

Though Poison Fruit is by no means a bad or subpar strain, it isn’t my personal favorite. I find it to be rather unremarkable in treating my depression/anxiety/ADD symptoms; though it definitely offers relief, I have found many other strains that do a better job of it.

I’d recommend this strain to patients who enjoy high-energy sativas and sativa-dominant hybrids; again, I really think this strain would be more of a fit for a sativa, rather than a hybrid.

Possibly good for treating:

  • Depression
  • Lack of motivation
  • Minor aches and pains
  • Minor gastrointestinal issues

I’m definitely no medical doctor, so please take the preceding conditions only as my own personal observations from using this strain and having experience with a multitude of different cannabis strains. Every body is different, and every body reacts different to various medications. 

Effects Rating: 3.80/5.00

Overall Rating: 3.60/5.00

Overall, I would best describe Poison Fruit as a “slightly above average” strain. 

This was a fairly enjoyable strain, but I think I’d prefer to go with Durban Posion – or even try Grapefruit, before buying this strain again. Every strain can’t be a homerun, but I will say that Trulieve has been staying consistent with the curing and moisture of their recent batches, and the overall quality of flower seems to be steadily rising throughout the State of Florida.

An important thing to remember: every body and every experience is different. Just because this strain wasn’t a personal favorite of mine does not mean it can’t or won’t be one of your favorites! One of the most fascinating aspects of medicating with cannabis is how individualized and different the various treatments can be from patient to patient. It’s more incentive to experiment, shop around, and find what works best for you personally! My one hope is that all these reviews help contribute to your overall medical cannabis experience in a positive way.

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As always, thank you for taking the time to read this review. Truly hope it helps you – we are here for you!


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